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Anti-Mouse IFN-Alpha, Rabbit Serum (PAb)

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Anti-Mouse IFN-Alpha, Rabbit Serum (PAb)

Catalog Number: 32100

Unconjugated Rabbit polyclonal antibody against Mouse IFN-Alpha suitable for use in Neutralization, ELISA, immunoprecipitation, and immunohistochemistry

$470.00

Pack Size
Product Info

SpecificityBinds to and neutralizes mouse IFN-Alpha
Tested Application
  • Neutralization
Suggested Applications*
  • ELISA
  • Immunoprecipitation
  • Immunohistochemistry

 

*Please note that these applications are presented for suggested use only and have not been fully evaluated by PBL

 

Immunized by E.coli expressed mouse interferon alpha A

Specifications

FormulationSupplied frozen as neat serum diluted in phosphate-buffered saline (PBS)
AntigenRecombinant mouse interferon alpha A (expressed in E.coli )
Host SpeciesRabbit
BioactivityMeasured by neutralization of interferon in cytopathic effect inhibition assay using L929 cells.
StorageFor retention of full activity store at -70oC or below and avoid repeated freeze/thaw cycles
Antigen SynonymsMouse IFN Alpha, Mouse IFN Alpha Rabbit Polyclonal, Interferon Alpha, IFN Alpha, IFN-a, Type I IFN Alpha

Citations

12 Citations

 

  1. Yin, X.T., et al.,  (2024), "UVB induced reactivation leads to HSV1 in the corneas of virtually all latently infected mice and requires STING to develop corneal disease", Sci Reports. 14:6859, DOI: 10.1038/s41598-024-52597-0 (link)
  2. Nagai, M, et al., (2023), "High body temperature increases gut microbiota-dependent host resistance to influenza A virus and SARS-CoV-2 Infection", Nat.Commun., 14(1):3863, PMID: 37391427, DOI: 10.1038/s41467-023-39569-0 (link)
  3. Marx, A. et. al., (2023), "The Alarmin interleukin-33 promotes the expansion and preserves the stemness of Tcf-1+ CD8+ T cells in chronic viral infection", Immunity, S1074-7613(23)0004-9, PMID: 36809763, DOI: 10.1016/j.immuni.2023.01.029 (link)
  4. von Buttlar, Heiner, et al. (2014). Identification of Toll-Like Receptor 9 as Parapoxvirus Ovis-Sensing Receptor in Plasmacytoid Dendritic Cells. PLOS One, 8 pgs. PMID: 25171368. (link)
  5. Woo, et al. (2013). Developmental Differences in IFN Signaling Affect GATA1s-Induced Megakaryocyte Hyperproliferation. JCI, 14 pgs. PMID: 23863621. (link)
  6. Winterberg, Pamela, et al. (2013). Reactive oxygen species and IRF1 stimulate IFNα production by proximal tubules during ischemic AKI. Renal Physiology, 9 pgs. PMID: 23657854. (link)
  7. Joshi, VD, et al. (2006). A role for Stat1 in the regulation of lipopolysaccharide-induced interleukin-1beta expression. Journal of Interferon & Cytokine Research. PMID: 17032168. (link)
  8. Publicover, Jean, et al. (2006). Rapid Pathogenesis Induced by a Vesicular Stomatitis Virus Matrix Protein Mutant: Viral Pathogenesis Is Linked to Induction of Tumor Necrosis Factor Alpha. JVI, 9 pgs. PMID: 16809308. (link)
  9. Benencia, Fabian, et al. (2005). HSV oncolytic therapy upregulates interferon-inducible chemokines and recruits immune effector cells in ovarian cancer. Molecular Therapy, 14 pgs. PMID: 15925544. (link)
  10. Pejawar, Sharmila, et al. (2005). Abortive versus Productive Viral Infection of Dendritic Cells with a Paramyxovirus Results in Differential Upregulation of Select Costimulatory Molecules. JVI, 14 pgs. PMID: 15919909. (link)
  11. Malmgaard, Lene, et al. (2004). Viral Activation of Macrophages through TLR-Dependent and -Independent Pathways. Journal of Immunology, 10 pgs. PMID: no PMID.
  12. Barchet, Winfried, et al. (2002). Virus-induced Interferon α Production by a Dendritic Cell Subset in the Absence of Feedback Signaling In Vivo. JEM, 10 pgs. PMID: 11854363. (link)

 

References

 

  1. Rubinstein, S., Familletti, P.C., and Pestka, S. (1981) "Convenient Assay for Interferons," J. Virol. 37, 755-758

Documentation

Certificate of Analysis (CoA) and Safety Data Sheet (SDS)
32100-1 CoA

32100-1 Certificate of Analysis

32100 SDS

32100 Safety Data Sheet